Doctors prescribe Rinvoq (upadacitinib) to treat certain inflammatory conditions, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). It’s available as an extended-release oral tablet and an oral solution known as Rinvoq LQ.

Rinvvoq belongs to the drug class known as Janus kinase (JAK) inhibitors. Generally, Medicare drug plans can cover Rinvoq. But whether they do or not and how much you must pay out of pocket depends on the specific plan.

You can get Medicare coverage for prescription drugs via a stand-alone Medicare Part D or a Medicare Advantage prescription drug (MAPD) plan. Private insurers manage these plans and set their coverage and costs.

According to the manufacturer’s website, experts have performed clinical trials involving Rinvoq for more than 11 years and have prescribed it to more than 100,000 people for RA in the United States since 2019.

With both types of drug coverage, your plan must cover at least two drugs from commonly prescribed drug categories. This means that Medicare drug plans may cover them. If they don’t, they often cover alternative drugs within the same categories with similar effectiveness.

You can check whether your specific plan covers Rinvoq by examining the plan’s formulary, which lists all the drugs the plan covers.

Without insurance, Rinvoq is a pricey drug. As of 2025, the list cost of a 30-day supply of the drug is $6,752.77.

If your Medicare drug plan covers the drug, how much you pay out of pocket depends on the drug’s tier within the plan’s formulary. Generally, generic drugs tend to be in lower tiers, costing less. However, currently there’s no generic version of Rinvoq.

That said, under a Medicare drug plan, you may never pay more than $2,000 out of pocket on prescription drugs per year in 2025. Once you reach this amount, your plan may cover the rest of your annual cost in full. This limit changes from year to year. In 2026, it may rise to $2,100.

In addition, no Medicare drug plan deductible can be higher than $590 in 2025.

If you need help with the costs of Rinvoq or Rinvoq LQ, with or without Medicare coverage, consider exploring NeedyMeds and the Medicine Assistance Tool. These sites offer details on drug assistance programs, savings cards, and more.

The drug’s manufacturer provides copay support via the Rinvoq Complete Savings Card, potentially lowering your cost to $0 per dose. However, you cannot use your Medicare coverage with this discount, and using the savings card might be cheaper than using your Medicare coverage.